Nivetha Murugesan Selected Research

Plasma Kallikrein

1/2022	Pharmacological suppression of the kallikrein kinin system with KVD900: An orally available plasma kallikrein inhibitor for the on-demand treatment of hereditary angioedema.
1/2022	KVD900, an oral on-demand treatment for hereditary angioedema: Phase 1 study results.
1/2019	Retinal proteome associated with bradykinin-induced edema.
1/2016	Plasma Kallikrein Mediates Vascular Endothelial Growth Factor-Induced Retinal Dysfunction and Thickening.
10/2015	Plasma Kallikrein-Kinin System as a VEGF-Independent Mediator of Diabetic Macular Edema.
9/2015	Thrombosis and Hemorrhage in Diabetic Retinopathy: A Perspective from an Inflammatory Standpoint.

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Nivetha Murugesan Research Topics

Disease

3	Macular Edema 01/2019 - 09/2015
3	Edema (Dropsy) 01/2019 - 09/2015
2	Hereditary Angioedemas 01/2022 - 01/2022
2	Inflammation (Inflammations) 01/2016 - 09/2015
2	Neuroinflammatory Diseases 08/2012 - 09/2009
1	Inborn Genetic Diseases (Disease, Hereditary) 01/2022
1	Pain (Aches) 01/2022
1	Papilledema 01/2016
1	Retinal Neovascularization 01/2016
1	Retinal Perforations 10/2015
1	Diabetic Retinopathy (Retinopathy, Diabetic) 09/2015
1	Ischemia 09/2015
1	Hemorrhage 09/2015
1	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 08/2012
1	Endotoxemia 09/2009

Drug/Important Bio-Agent (IBA)

6	Plasma KallikreinIBA 01/2022 - 09/2015
3	Retinaldehyde (Retinal)IBA 01/2019 - 09/2015
2	BradykininIBA 01/2022 - 01/2019
2	sebetralstatIBA 01/2022 - 01/2022
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2016 - 10/2015
1	Hormones (Hormone)IBA 01/2022
1	High-Molecular-Weight Kininogen (Kininogen, High Molecular Weight)IBA 01/2022
1	ProteomeIBA 01/2019
1	Oxygen (Dioxygen)IBA 01/2016
1	Serine Proteases (Serine Protease)IBA 01/2016
1	PrekallikreinIBA 10/2015
1	KininsIBA 10/2015
1	Thrombin FDA Link 09/2015
1	Urokinase-Type Plasminogen Activator (Urokinase)FDA Link 09/2015
1	Blood Coagulation Factors (Coagulation Factor)IBA 09/2015
1	Myelin-Oligodendrocyte GlycoproteinIBA 08/2012
1	Peptides (Polypeptides)IBA 08/2012
1	Pharmaceutical PreparationsIBA 09/2009
1	LipopolysaccharidesIBA 09/2009

Therapy/Procedure

1	Lasers (Laser) 09/2009
1	Therapeutics 09/2009